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Trichomonas vaginalis Weakens Human Amniochorion in an In Vitro Model of Premature Membrane Rupture

By Deborah Draper, Ward Jones, R. Phillip Heine, Michelle Beutz, Janice I. French and James A. McGregor

Abstract

Objective: Trichomonas vaginalis (TV) infection is associated with preterm rupture of membranes (PROM) and preterm birth. We evaluated the effects of TV growth and metabolism on preparations of human amniochorion to understand and characterize how TV may impair fetal-membrane integrity and predispose to PROM and preterm birth

Topics: Research Article
Publisher: Hindawi Publishing Corporation
OAI identifier: oai:pubmedcentral.nih.gov:2364407
Provided by: PubMed Central
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    1. (1984). A: Pathogenicity of Trichomonas vaginalis: Cytopathologic and histopathologic changes of the cervical epithelium.
    2. (1985). Adjunctive erythromycin treatment for idiopathic preterm labor: Results of a randomized, doubleblinded, placebo-controlled trial.
    3. (1990). Alderete JF: Analysis of the proteinases of representative Trichomonas vaginalis isolates. Infect Immun 58:157-162,
    4. (1987). An agar culture technique to quantitate Trichomonas vaginalis from women.
    5. Antibody in sera of patients infected with Trichomonas vaginalis is to trichomonad proteinases.
    6. (1989). Bacteria and inflammatory cells reduce chorioamnionic membrane integrity and tensile strength. Obstet Gynecol 74:590-596,
    7. (1989). Biochemistry of Trichomons vaginalis.
    8. (1989). Clinical manifestation of urogenital trichomoniasis in women.
    9. Cytopathology and histopathology of the female genital tract in Trichomonas vaginalis infection.
    10. (1991). Demographic and behavioral predictions of Trichomonas vaginalis infection among pregnant women.
    11. (1986). EL: Protease production by microorganisms associated with reproductive tract infection.
    12. G: Collagen content of human amniotic membranes: Effect of gestational length and premature rupture.
    13. (1987). GH: The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads.
    14. Hoerner JK: The role of infection in premature rupture of membranes.
    15. (1986). JK: In vitro study of bacterial protease induced reduction of chorioamnionic membrane strength and elasticity. Obstet Gynecol 69:167-174,
    16. Klykken PC: Characterization of a secreted cytoactive factor from Trichomonas vaginalis.
    17. (1991). Pastorek JG: Effect of Trichomonas vaginalis (TV) carriage on pregnancy outcome. Presented at the International Society for Sexually Transmitted Diseases,
    18. (1984). Pearlman E: Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers.
    19. (1980). Peters EC: Causes and consequences of premature rupture of fetal membranes. Lancet 1:192,
    20. (1985). Phospholipase C production by microorganisms associated with female upper genital tract infection. Society for Gynecologic Investigation,
    21. (1984). Prevalance of six sexually transmitted disease agents among pregnant inner city adolescents and pregnancy outcomes.
    22. (1989). Prevention of microbial induced impairment of amniochorion by specific protease inhibitor. Society for Perinatal Obstetricians,
    23. (1988). Prevention of preterm birth: New initiatives based on microbial host interactions. Obstet Gynecol Surv 43:1-14,
    24. (1985). Rein MF: Contact-dependent cytopathogenic mechanisms of Trichomonas vaginalis.
    25. (1984). Risk factors for prematurity and premature rupture of membranes: A prospective study of vaginal flora in pregnancy.
    26. (1992). RL: A review of premature birth and subclinical infection.
    27. (1985). The contribution of low birthweight to infant mortality and childhood morbidity.
    28. (1989). WR: Isolation of a cell detaching factor of Trichomonas vaginalis.
    29. (1990). WR: The effect of Trichomonas vaginalis and the role ofpH on cell culture monolayer viability. Clin Invest Med 13(2):71-76,

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