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New Incoherent Autofluorescence/Fluorescence System for Early Detection of Lung Cancer

By Martin Leonhard


A new autofluorescence (AF) system for bronchoscopy that operates as compact as a conventional white light bronchoscopy system is described. The system is also capable of white light illumination and excitation of aminolevulinic acid (ALA) induced fluorescence. Changing between white light and (auto-) fluorescence mode is easy and always possible. Broad band excitation with blue light (AF: 380–460 nm; ALA 380–440 nm) delivers high intensity illumination at the distal end of the bronchoscope (AF typically 50 mW). A special optical observation technique makes the AF directly visible to the eye instead of indirect techniques used in other AF systems. A compact (160 g)and sensitive (typically 0.2 lux) camera can be used for documentation

Topics: Research Article
Publisher: Hindawi Publishing Corporation
OAI identifier: oai:pubmedcentral.nih.gov:2362615
Provided by: PubMed Central
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    1. (1998). ALAinduced fluorescence and autofluorescence bronchoscopy in detection oflung cancer.
    2. (1995). Fluorescence cystoscopy following intravesical instillation of5-aminolevulinic acid: A new procedure with high sensitivity for detection ofhardly visible urothelial neoplasis.
    3. (1994). Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid. Urology
    4. (1996). Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer.
    5. (1998). Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. Neurosurgery
    6. (1998). Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. Chest
    7. (1998). Spectral data reproduced with kind permisson
    8. (1998). The result ofa pilot study with an autofluorescence bronchoscopy system, lOth WormCongressfor Bronchology,

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