NUMEROUS sulfa drugs have been found valuable in the prevention and treatment of coccidiosis in poultry. Also various methods of using these drugs have been recommended. It is the belief of the authors that the inclusion of the medication in the feed continuously over a sufficient period of time to allow immunity to develop from natural expos-ure would be the safest and most eco-nomical method for controlling coccidiosis. This procedure would call for controlled infection rather than complete prevention of infection in order that the desired immunity might be established. Work at this station (Delaplane et al. 1947, and Grumbles el al. 1947) has shown that sulfaquinoxaline is effective against both cecal and intestinal coccidiosis. In these experiments 0.05 percent sulfa-quinoxaline, fed in mash intermittently, and 0.033 and 0.0125 percent, fed con-tinuously in mash, gave good results. These studies also have shown that sulfa-quinoxaline used thus did not prevent the development of resistance to Eimeria tenella and Eimeria necatrix. MATERIALS AND METHODS This work was conducted in the field with the cooperation of a commercial * These studies were made possible by a gran
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