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P11-M Comprehensive and Reliable Proteome Analysis Using Bioinformatic Strategies for Automated Result Validation

By M. Macht, C. Albers, K. Sparbier, A. Asperger, J. Glandorf and H. Thiele

Abstract

Proteomic analyses typically produce massive amounts of mass spectrometric data, which are analyzed in an automated way by database search engines for retrieval of peptide sequences and subsequent inference on the corresponding protein sequences. However, this process turned out to be error prone, producing false positives and multiple hits for the same proteins for various reasons

Topics: Poster Abstracts: Bioinfomatics
Publisher: The Association of Biomolecular Resource Facilities
OAI identifier: oai:pubmedcentral.nih.gov:2291870
Provided by: PubMed Central
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