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Prognostic Indicators of Changes in Bone Density Measures in Adolescent Girls with Anorexia Nervosa-II

By Madhusmita Misra, Rajani Prabhakaran, Karen K. Miller, Mark A. Goldstein, Diane Mickley, Laura Clauss, Patrice Lockhart, Jennalee Cord, David B. Herzog, Debra K. Katzman and Anne Klibanski

Abstract

Introduction: Adolescents with anorexia nervosa (AN) have low bone mineral density (BMD). Baseline predictors of temporal BMD changes (ΔBMD) in AN, including 1) gastrointestinal peptides regulating food intake and appetite that have been related to bone metabolism and 2) bone turnover markers, have not been well characterized. We hypothesized that baseline levels of nutritionally regulated hormones and of bone turnover markers would predict ΔBMD overall

Topics: Original Article
Publisher: The Endocrine Society
OAI identifier: oai:pubmedcentral.nih.gov:2291487
Provided by: PubMed Central
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