Occupational risk assessment of aspergillosis after renal transplantation

Abstract

Returning to work after transplantation is a much-discussed topic today, especially as a measure to avoid permanent work disability. Many transplant patients regain their ability to work 2-6 months after transplantation. However, returning to work should not endanger their health. This means that occupational risks such as occupational exposure to Aspergillus spores must be evaluated. We evaluated the community-acquired aspergillosis risk and in particularly the occupational aspergillosis risk, using the example of a 39-year-old construction worker immunosuppressed after renal transplantation. On one hand the risk is linked to the exposure to microorganisms that the individual is likely to be subjected to, and on the other hand to the factors that modify his state of susceptibility or resistance to these infectious agents. The necessity of immunosuppressive therapy after transplantation elevates the aspergillosis risk, especially 1-6 months after transplantation. There are many professions in which exposure to Aspergillus spores can occur. The risk of acquiring aspergillosis at work exists, but is not quantifiable today. Nevertheless, the risk should be minimized during the period of vulnerability by preventive measures such as restriction of certain activities, changing work methods and reorganizing the work day to adapt to the risk, and wearing personal protective equipment, as well as attention to information about aspergillosis risk and about the likelihood of exposure in the patient's professional and leisure activities. [Authors]]]> Kidney Transplantation ; Aspergillosis ; Occupational Exposure ; Lung Diseases, Fungal ; Risk Assessment ; Aspergillus eng oai:serval.unil.ch:BIB_53334448DDE3 2025-08-02T01:29:31Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_53334448DDE3 GTH 2021: The First Online Experience! Useful for Future Meetings? info:doi:10.1055/a-1441-6233 info:eu-repo/semantics/altIdentifier/doi/10.1055/a-1441-6233 info:eu-repo/semantics/altIdentifier/pmid/33860517 Alberio, L. info:eu-repo/semantics/article article 2021-04 Hamostaseologie, vol. 41, no. 2, pp. 100-102 info:eu-repo/semantics/altIdentifier/eissn/2567-5761 urn:issn:0720-9355 eng oai:serval.unil.ch:BIB_532BB9660ED8 2025-08-02T01:29:31Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_532BB9660ED8 Effect of a pathological scapular tilt after total shoulder arthroplasty. info:doi:10.1080/10255842.2012.656612 info:eu-repo/semantics/altIdentifier/doi/10.1080/10255842.2012.656612 info:eu-repo/semantics/altIdentifier/pmid/22375919 Röthlisberger, M. Pioletti, D.P. Farron, A. Terrier, A. info:eu-repo/semantics/article article 2013 Computer Methods in Biomechanics and Biomedical Engineering, vol. 16, no. 11, pp. 1196-1201 info:eu-repo/semantics/altIdentifier/eissn/1476-8259 urn:issn:1025-5842 <![CDATA[Total shoulder arthroplasty (TSA) is an accepted and most successfully used treatment for different shoulder pathologies. Different risk factors for the failure of the prosthesis are known. A pathological scapular orientation, observed in elderly people or in patients suffering from neuromuscular diseases, could be a cause of failure, which has not been investigated yet. To test this hypothesis, a numerical musculoskeletal model of the glenohumeral joint was used to compare two TSA cases: a reference normal case and a case with a pathological anterior tilt of the scapula. An active abduction of 150° was simulated. Joint force, contact pattern, polyethylene and cement stress were evaluated for both cases. The pathological tilt slightly increased the joint force and the contact pressure, but also shifted the contact pattern. This eccentric contact increased the stress level within the polyethylene of the glenoid component and within the surrounding cement layer. This adverse effect occurred mainly during the first 60° of abduction. Therefore, a pathological orientation of the scapula may increase the risk of a failure of the cement layer around the glenoid component. These preliminary numerical results should be confirmed by a clinical study