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Hierarchically structured materials for bone regenerations: biomimetic morphology, micro-mechanics and properties

By S. Henning, H. R. Imam Khasim, G. H. Michler and J. Brandt


The contribution describes the development of a biocompatible nanocomposite material consisting of a resorbable polymeric matrix and osteoinductive nanoparticles that can be used to manufacture compact products, porous scaffolds, hybrid nanofibers, and alternating porous/compact structures. It is shown that the material has a good balance of stiffness, strength and toughness. The material supports osteoblast proliferation. Based on a modular design principle, several prototypes for hierarchical 3D constructs are proposed

Topics: bone regeneration, micromechanics, nanostructured biomaterials
Year: 2012
DOI identifier: 10.1002/masy.201250511
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Provided by: Fraunhofer-ePrints
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