Module assembly technology to manufacture effervescent tablets in a non dehumidified production plant

Abstract

none6noDome Matrix® platform can combine 2-3 drugs into a unit oral dosage form based on module assembly strategy, to simplify complex therapies. As the assembly size increases, dispersion in water before administration may be desirable. Here, excipient modules were studied for promoting assembly dispersion by effervescence obtained by introducing the reagents or drugs in separated modules.noneTorre, E.; Bonazza, I.; Balducci, A.G.; Colombo, P.; Sonvico, F.; Colombo, G.Torre, E.; Bonazza, Ilaria; Balducci, A. G.; Colombo, P.; Sonvico, F.; Colombo, Gai