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Improving cardiac myocytes performance by carbon nanotubes platforms

By Valentina Martinelli, Giada Cellot, Alessandra Fabbro, Susanna Bosi, Luisa Mestroni and Laura Ballerini


The application of nanotechnology to the cardiovascular system has increasingly caught\ud scientists’ attention as a potentially powerful tool for the development of new generation\ud devices able to interface, repair, or boost the performance of cardiac tissue. Carbon\ud nanotubes (CNTs) are considered as promising materials for nanomedicine applications in\ud general and have been recently tested toward excitable cell growth. CNTs are cylindrically\ud shaped structures made up of rolled-up graphene sheets, with unique electrical,\ud thermal, and mechanical properties, able to effectively conducting electrical current in\ud electrochemical interfaces. CNTs-based scaffolds have been recently found to support\ud the in vitro growth of cardiac cells: in particular, their ability to improve cardiomyocytes\ud proliferation, maturation, and electrical behavior are making CNTs extremely attractive for\ud the development and exploitation of interfaces able to impact on cardiac cells physiology\ud and function

Topics: Cardiac tissue engineering, Cardiomyocyte maturation, Cardiomyocyte proliferation, Nanotechnology, Synthetic interface, Physiology, Physiology (medical)
Year: 2013
DOI identifier: 10.3389/fphys.2013.00239
OAI identifier:

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