research article
oaioai:arts.units.it:11368/1855549

A simple method for the preparation of PEG-6-mercaptopurine for oral administration

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Publication date
1 January 2007
Publisher
Doi

    Abstract

    A new and efficient method for the synthesis of PEG-6-mercaptopurine is described. The key feature of the proposed approach is the protection of the thiol group against metabolic inactivation. Preliminary in vivo and in vitro evaluations of the macromolecular prodrug have been carried out

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    Archivio istituzionale della ricerca - Università di Trieste

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    Last time updated on 12/11/2016

    This paper was published in Archivio istituzionale della ricerca - Università di Trieste.

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