Article thumbnail
Location of Repository

Hydrolysis of ITP generates a membrane potential in submitochondrial particles.

By Sorgato MC, Galiazzo F, Valente M, Cavallini L and Ferguson SJ

Abstract

ITP hydrolysis catalysed by the ATPase of submitochondrial particles from both bovine heart and rat liver is shown to be linked to the generation of a membrane potential, and therefore also to proton translocation. The magnitude of the membrane potential is similar to that observed during ATP hydrolysis at equivalent concentrations of phosphate and nucleoside tri- and diphosphates. An explanation is suggested for why in other reports ITP was found to be a poor substrate for supporting energy-linked reactions that are driven by the membrane potential

Year: 1982
DOI identifier: 10.1016/0005-2728(82)90038-X
OAI identifier: oai:www.research.unipd.it:11577/2516808
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://hdl.handle.net/11577/25... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.