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Biofortification of UK food crops with selenium \ud

By Martin R. Broadley, Philip J. White, Rosie J. Bryson, Mark C. Meacham, Helen C. Bowen, Sarah E. Johnson, Malcolm J. Hawkesford, Steve P. McGrath, Fang-Jie Zhao, Neil Breward, Miles Harriman and Mark Tucker


Se is an essential element for animals. In man low dietary Se intakes are associated with health disorders including oxidative stress-related conditions, reduced fertility and immune functions and an increased risk of cancers. Although the reference nutrient intakes for adult females and males in the UK are 60 and 75 μg Se/d respectively, dietary Se intakes in the UK have declined from >60 μg Se/d in the 1970s to 35 μg Se/d in the 1990s, with a concomitant decline in human Se status. This decline in Se intake and status has been attributed primarily to the replacement of milling wheat having high levels of grain Se and grown on high-Se soils in North America with UK-sourced wheat having low levels of grain Se and grown on low-Se soils. An immediate solution to low dietary Se intake and status is to enrich UK-grown food crops using Se fertilisers (agronomic biofortification). Such a strategy has been adopted with success in Finland. It may also be possible to enrich food crops in the longer term by selecting or breeding crop varieties with enhanced Se-accumulation characteristics (genetic biofortification). The present paper will review the potential for biofortification of UK food crops with Se

Topics: S1, SB
Publisher: Cambridge University Press
Year: 2006
OAI identifier: oai:wrap.warwick.ac.uk:697

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  1. (2005). A fresh look at bread.
  2. (1998). A review of selenium deficiency in grazing ruminants. part 1: New roles for selenium in ruminant metabolism.
  3. (2001). Addressing micronutrient malnutrition through enhancing the nutritional quality of staple foods: principles, perspectives and knowledge gaps.
  4. (1990). Application of selenium prills to improve the selenium supply to a grass clover sward.
  5. (2004). Are there functional consequences of a reduction in selenium intake in UK subjects?
  6. (1988). Aro A & Koivistoinen P
  7. (1969). Broadley et al.Cary EE & Allaway WH
  8. (1964). Broadley et al.Rosenfeld I & Beath OA
  9. (2001). Changes in selenium, zinc, copper and cadmium contents in human milk during the time when selenium has been supplemented to fertilizers in Finland.
  10. (1981). Changes of blood selenium in New Zealand adults with time and importation of Australian wheat.
  11. (2002). Characterization of selenium species in Brazil nuts by HPLCICP-MS and ES-MS.
  12. (2003). Chemical form and distribution of selenium and sulfur in the selenium hyperaccumulator Astragalus bisulcatus.
  13. (1987). Chemical-equilibria of selenium in soils – a theoretical development.
  14. (1986). Comparison of selenium treatments of crops in the field.
  15. (1992). Contrasting selenatesulfate interactions in selenium-accumulating and nonaccumulating plant species.
  16. (1977). Control of selenium in plants.
  17. (2005). Current evidence and research needs to support a health claim for selenium and cancer prevention.
  18. (1999). Current issues in trace element nutrition of grazing livestock in Australia and New Zealand.
  19. (1998). Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial.
  20. (2002). Determination of selenium concentration of rice in China and effect of fertilization of selenite and selenate on selenium content of rice.
  21. (1997). Dietary selenium: time to act.
  22. (1995). Dissociation of the genotoxic and growthinhibitory effects of selenium.
  23. (2003). Distribution and management of seleniferous soils.
  24. (2001). Ecotypic variation in selenium accumulation among populations of Stanleya pinnata.
  25. (1982). Effect of applied selenium on the selenium content of barley and forages and soil selenium depletion rates.
  26. (1989). Effect of selenate vs selenite forms of selenium in increasing the selenium concentration in forages and cereals.
  27. (1984). Effect of selenite and selenate fertilization and foliar spraying on selenium content of timothy grass.
  28. (1984). Effect of selenium fertilization and foliar spraying at different growth-stages on the selenium content of spring wheat and barley.
  29. (1996). Effect of selenium fertilization on selenium in feedstuffs and selenium, vitamin E, and b-carotene concentrations in blood of cattle.
  30. (1997). Effect of selenium supplementation on the selenium content in muscle and liver of Finnish pigs and cattle.
  31. (1994). Effect of selenium-enriched calcium nitrate, top-dressed at different growth-stages, on the selenium concentration in wheat.
  32. (2003). Effect of the application of selenium on selenium content of soybean and its products.
  33. (1994). Effect of various sources of selenium fertilization on the selenium concentration of feed crops.
  34. (1995). Effects of Selcote1 Ultra and sodium selenate (laboratory versus commercial grade) on selenium concentration in feed crops.
  35. (1989). Effects of selenium fertilization on the selenium content of selected Finnish fruits and vegetables.
  36. (1998). Effects of selenium supplementation of field crops.
  37. (1990). Effects of soil application of selenium on pasture composition.
  38. (1995). Effects of supplementation of fertilizers on human selenium status in Finland.
  39. (1987). Eh-pH Diagrams for Geochemistry.
  40. (2003). Enhanced selenium tolerance and accumulation in transgenic Arabidopsis expressing a mouse selenocysteine lyase.
  41. (2004). Enhancing the nutritional value of plant foods 179Hanson B, Lindblom SD,
  42. (1995). Environmental effects of nationwide selenium fertilization in Finland.
  43. (2002). Evidence of low selenium concentrations in UK bread-making wheat grain.
  44. (2004). Exploiting micronutrient interaction to optimize biofortification programs: The case for inclusion of selenium and iodine in the HarvestPlus program.
  45. (2005). Exploring natural genetic variation to improve plant nutrient content.
  46. (2005). Field trial of transgenic Indian mustard plants shows enhanced phytoremediation of selenium-contaminated sediment.
  47. (2001). Genetic variances and selection potential for selenium accumulation in a rapid-cycling Brassica oleracea population.
  48. (2003). Genetically modified food crops and their contribution to human nutrition and food quality.
  49. (2003). High-selenium wheat: biofortification for better health.
  50. (2005). Historical variation in the mineral composition of edible horticultural products.
  51. (1984). Improvement of selenium status of pasture crops.
  52. (2004). Interactions between selenium and sulphur nutrition in Arabidopsis thaliana.
  53. (1994). Lahermo P & Va ¨a ¨na ¨nen P
  54. (1993). Long-term change in the biogeochemical cycling of atmospheric selenium: deposition to plants and soil.
  55. (1981). Long-term residual effects of applied selenium on the selenium uptake by plants.
  56. (2005). Mapping nutritional traits in crop plants.
  57. (2003). Mechanism and regulation of selenoprotein synthesis.
  58. (2003). Micronutrient fortification of plants through plant breeding: can it improve nutrition in man at low cost?
  59. (1956). Ministry of Housing and Local Government
  60. (2002). New concepts in selenium chemoprevention.
  61. (1969). Notes on hair and nail loss after ingesting Sapucaia Nuts (Lecythis elliptica).
  62. (1999). Overexpression of ATP sulfurylase in Indian mustard leads to increased selenate uptake, reduction, and tolerance.
  63. (2004). Overexpression of selenocysteine methyltransferase in Arabidopsis and Indian mustard increases selenium tolerance and accumulation.
  64. (2003). Plants, selenium and human health.
  65. (1983). Prevention of selenium deficiency in grazing animals by annual topdressing of pasture with sodium selenate.
  66. (2002). Quality of animal and human life as affected by selenium management of soils and crops.
  67. (2000). Quantitative, chemically specific imaging of selenium transformation in plants.
  68. (1984). Raising the selenium content of spring wheat and barley using selenite and selenate.
  69. (1967). Reactions of selenite-selenium added to soils that produce low-selenium forages.
  70. (2004). Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution.
  71. (1992). rock-soil-human system.
  72. (2002). Selenate-resistant mutants of Arabidopsis thaliana identify Sultr1;2, a sulfate transporter required for efficient transport of sulfate into roots.
  73. (2003). Selenium accumulation protects Brassica juncea from invertebrate herbivory and fungal infection.
  74. (2002). Selenium and its redox speciation in rainwater from sites of Valparaiso region in Chile, impacted by mining activities of copper ores.
  75. (2004). Selenium and its relationship to cancer: an update.
  76. (1957). Selenium as an integral part of factor-3 against dietary necrotic liver degeneration.
  77. (1998). Selenium concentration in plant material, drainage and surface water as influenced by Se applied to barley foliage in a barleyred clover-potato rotation.
  78. (2005). Selenium concentration in wheat grain: Is there sufficient genotypic variation to use in breeding?
  79. (2002). Selenium concentration of fescue and bahia grasses after applying a selenium fertilizer.
  80. (1973). Selenium content of field crops grown on selenite-treated soils.
  81. (2004). Selenium content of Finnish oats in 1997–1999: effect of cultivars and cultivation techniques.
  82. (2005). Selenium deficiency and toxicity in the environment.
  83. (1994). Selenium fertilizers for pastures grazed by sheep. 1. Selenium concentrations in whole-blood and plasma.
  84. (1994). Selenium fertilizers for pastures grazed by sheep. 2. Wool and liveweight responses to selenium.
  85. (1991). Selenium in Finnish foods after beginning the use of selenate supplemented fertilizers.
  86. (2000). Selenium in higher plants.
  87. (1984). Selenium in soils and plants and its importance in livestock and human nutrition.
  88. (1984). Selenium speciation in the soil solution and its relevance to plant uptake.
  89. (2003). Selenium supplementation: does soil supplementation help and why?
  90. (1997). Short-day onion cultivars differ in bulb selenium and sulfur accumulation which can affect bulb pungency.
  91. (1992). Soil selenium treatments to ameliorate selenium deficiency in herbage.
  92. (1989). Solubility, speciation and transformation of selenium in soils.
  93. Stangoulis JCR & Graham RD (2005b) Tolerance of wheat (Triticum aestivum L.) to high soil and solution selenium levels.
  94. (2005). Studying the distribution pattern of selenium in nut proteins with information obtained from SEC-UV-ICP-MS and CE-ICP-MS.
  95. (2002). The argument for increasing selenium intake.
  96. (1996). The changing selenium status of New Zealand residents.
  97. (1966). The depilatory and cytotoxic actions of ‘Coco de Mono’ (Lecythis ollaria) and its relationship to chronic selenosis.
  98. (1999). The distribution and origin of trace elements in a UK coal; the importance of pyrite.
  99. (1997). The effect of sulphur/ nitrogen/selenium interactions on herbage yield and quality.
  100. (1989). The effects of sodium selenate applications on growth and selenium concentration in wheat.
  101. (1995). The impact of selenium supplemented fertilization on selenium in lake ecosystems in Finland.
  102. (2000). The importance of selenium to human health.
  103. (1996). The nutritional prevention of cancer with selenium 1983–1993: a randomized clinical trial.
  104. (2000). The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana.
  105. (1998). The serum selenium concentrations in children and young adults: a long-term study during the Finnish selenium fertilization programme.
  106. (1970). The uptake of applied selenium by agricultural plants. 2. The utilization of various selenium compounds.
  107. (2004). The use of high-selenium yeast to raise selenium status: how does it measure up?
  108. (2003). Transcriptome profiling of sulfur-responsive genes in Arabidopsis reveals global effects of sulfur nutrition on multiple metabolic pathways.
  109. (2003). Transporter gene families in plants: the sulphate transporter gene family-redundancy or specialization?
  110. (2002). Two distinct high-affinity sulfate transporters with different inducibilities mediate uptake of sulfate in Arabidopsis roots.
  111. (1962). Uptake and assimilation of selenite by higher plants.
  112. (1999). Uptake and distribution of selenium in tomato plants as affected by genotype and sulphate supply.
  113. (2003). Uptake and transport of selenite and selenate by soybean seedlings of two genotypes. Plant and Soil 253, 437–443. Enhancing the nutritional value of plant foods 181
  114. (1966). Uptake of native and applied selenium by pasture species I. Uptake of Se by browntop, ryegrass, cocksfoot, and white clover from Atiamuri sand.
  115. (1967). Uptake of native and applied selenium by pasture species. 4. Relative uptake through foliage and roots by white clover and browntop. Distribution of selenium in white clover.
  116. (1989). Uptake of selenite fertilizer by subterranean clover pasture in Western Australia.
  117. (1990). Variation in [ 75Se]selenate uptake and partitioning among tomato cultivars and wild species.

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