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Arq Neuropsiquiatr

By Pedro A. P. Jesus, Rodrigo M. Vieira de Melo, Francisco J. F. B. Reis, Leila C. Viana, Amanda Lacerda, Jesangeli S. Dias and Jamary Oliveira Filho


P.207-210Cognitive symptoms are common in patients with congestive heart failure (CHF) and are usually attributed to low cerebral blood flow. In the present study, we aimed to evaluate global cognitive function (Mini Mental State Exam - MMSE) in relation to both cardiac function (evaluated by echocardiogram) and cere b rovascular hemodynamics (evaluated by transcranial Doppler - TCD) in CHF patients. In 83 patients studied, no correlation was found between echocardiographic parameters and MMSE scores. In contrast, a significant correlation was found between right middle cerebral art e ry (RMCA) mean flow velocity and MMSE score (r=0.231 p=0.039), as well as between RMCA pulsatility index and MMSE score (rs= –0.292 p=0.015). After excluding patients with a previous history of stroke, only RMCA pulsatility index c o rrelated with MMSE score (rs=–0,314 p=0,007). The relationship between high cere b rovascular resistance and worse cognitive scores suggest that microembolism may be Responsible for a significant pro p o rtion of cognitive symptoms in CHF patients

Topics: Transcranial Doppler, Congestive heart failure, Cognitive dysfunction cerebrovascular disorders
Publisher: Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange
Year: 2006
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