Skip to main content
Article thumbnail
Location of Repository

Prenatal exposure to cadmium and cotinine and CpG island DNA methylation in mother–infant pairs

By Saideep Gona, Alison P. Sanders, Marie Lynn Miranda and Rebecca C. Fry


A precise biological mechanism by which cadmium acts as a developmental toxicant is unknown but is suggested to include an epigenetic basis. In prior work, we analyzed CpG island methylation levels within gene promoters (n = 16,421) in leukocytes collected from mothers and their infants from a pregnancy cohort in Durham County, North Carolina. The CpG methylation levels were examined in relationship to prenatal exposure to cadmium and/or cotinine to identify genes and pathways influenced by in utero exposure. In the present article, we provide an enhanced description of the data collection and processing to facilitate cross-study comparisons. Data are available within the Gene Expression Omnibus database (GSE67976)

Topics: Genetics, QH426-470
Publisher: Elsevier
Year: 2015
DOI identifier: 10.1016/j.gdata.2015.07.001
OAI identifier:
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.