FRAKSINASI EKSTRAK METANOL KULIT BATANG Rhizophora mucronata DAN UJI DAYA HAMBATNYA TERHADAP BAKTERI Escherichia coli

Abstract

Rhizhophora mucronata is commonly found mangrove plant due to it’s wide distribution. The bark of this plant used for traditional medicine as slimming, antidiarrhea , anticonstipation. The chemical compounds of R. mucronata are tannins, alcaloide, flavanoids and saponin. In order to find out the effect of chemical activity of this plant, a research entitled Fractionation Metanol Extracts Bark of R. Mucronata and Inhibiting Capacity Assay against Escherichia coli Bacteria has been carried out. The bark of R. mucronata was extracted by soxhlet with methanol solvent. Than methanol extract was fractionated with developing solvent kloroform : metanol (1:9) and producing five fractions that gave positive result on test for alcaloide compounds. The result of infrared spectroscopy that fraction 1-5 also contains of alcaloide. All fractions from coulomn chromatography tested on E. coli with dilution method which gave result that these fractions inhibit the growth of E. coli