Prevalence of hypothyroidism among children and adolescents with diabetes mellitus by results of selective screening

Abstract

Establish the prevalence of hypothyroidism among children with diabetes mellitus (DM) as a result of selective screening. During the examination period 132 children (64 f/68 m) aged from 1.0 to 17.5 years were examined. Ultrasonography evaluation, including measurement of thyroid volume, was performed in all volunteers as well as analysis of TSH, TPOAb and fT4 when TSH was out of reference range. The prevalence of overt hypothyroidism (7,6%) in the outcome of AIT in children with DM was above the population level, which confirms the effective of selective screening in this group of children and demands to its introduction into routine clinical practice; high incidence of TPOAb (12.8%) need to clarify their prognostic value having regard to longterm followup, as well as revising of dividing cutofpoint