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IN VITRO IMMUNOTROPICITY STUDIES OF POLYFUNCTIONAL WATER-SOLUBLE ANTIOXIDANTS

By S. Yu. Klepikova, O. P. Kolesnikova, A. Ye. Prossenko and N. V. Kandalintceva

Abstract

<p><strong>Abstract.</strong> A study of immunotropic properties of ω-(3,5-dimethyl-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-11-7), and ω-(3,5-di-tret-butil-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-17-7) was carried out, employing an in vitro model of spontaneous and mitogen- stimulated proliferation of cultured spleen cells. It is revealed, that the F-11-7 and F-17-7 compounds are able to suppress proliferation of intact splenocytes in a dose-dependent manner. <strong><em>(Med. Immunol., 2008, vol. 10, n 2-3, pp 269-272)</em></strong>.</p

Topics: водорастворимые антиоксиданты, иммунотропные препараты, Immunologic diseases. Allergy, RC581-607
Publisher: SPb RAACI
Year: 2008
OAI identifier: oai:doaj.org/article:72e0742a5a2e49ceb9b55d01b450bb59
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