oaioai:doaj.org/article:72e0742a5a2e49ceb9b55d01b450bb59

IN VITRO IMMUNOTROPICITY STUDIES OF POLYFUNCTIONAL WATER-SOLUBLE ANTIOXIDANTS

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Publication date
1 July 2014
Publisher
'SPb RAACI'
Doi

    Abstract

    Abstract. A study of immunotropic properties of Ο‰-(3,5-dimethyl-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-11-7), and Ο‰-(3,5-di-tret-butil-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-17-7) was carried out, employing an in vitro model of spontaneous and mitogen- stimulated proliferation of cultured spleen cells. It is revealed, that the F-11-7 and F-17-7 compounds are able to suppress proliferation of intact splenocytes in a dose-dependent manner. (Med. Immunol., 2008, vol. 10, n 2-3, pp 269-272)

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