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Monitoring of vascular dysregulation in normotensive glaucoma

By E. M. Kasimov, M. E. Efendiyeva and A. N. Mamedzade

Abstract

<p><strong>Purpose:</strong> To study blood flow autoregulation in normotensive glaucoma using ultrasound dopplerography before and after a neuroprotective<br />treatment.</p><p><br /><strong>Methods:</strong> In the period of observation from 2010 to 2012, we examined 94 patients (183 eyes), of which 33 (61 eyes) — with normotensive glaucoma (NG), 31 (62 eyes) — with open-angle glaucoma (OAG) and 30 patients (60 eyes) was the control group. There were 40 men and women — 54. Mean age was 58.5±6.5 years.</p><p><br /><strong>Results:</strong> Ultrasound dopplerography showed marked reduction of peak systolic, terminal diastolic velocity and an increase in resistance index CRA and SPCA (p &lt;0.001) and OA (p &lt;0.05) in the group of patients with NG compared to the norm.</p><p><br /><strong>Conclusion:</strong> There is a certain tendency to improvement of hemodynamic parameters after treatment with neuroprotective that at the root does not negate the need for neuroprotection in NG.</p

Topics: нормотензивная глаукома, допплерография,, нейропротекция, Ophthalmology, RE1-994
Publisher: Ophthalmology Publishing Group
Year: 2013
OAI identifier: oai:doaj.org/article:6604177a575b44c8a287e8c47660e76a
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