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oaioai:centaur.reading.ac.uk:37106

Zinc mediated azide-alkyne ligation to 1,5- and 1,4,5-substituted 1,2,3-triazoles

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Publication date
3 September 2013
Publisher
The American Chemical Society
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    Abstract

    A mild method for regioselective formation of 1,5-substituted 1,2,3-triazoles is described. The zinc-mediated reaction works at room temperature and is successful across a wide range of azido/alkynyl substrates. Additionally, the triazole 4-position can be further functionalized through the intermediate aryl-zinc to accommodate a diverse three-component coupling strategy

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      Central Archive at the University of Reading

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      Last time updated on 28/07/2016

      This paper was published in Central Archive at the University of Reading.

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