Skip to main content
Article thumbnail
Location of Repository

Inhibition by N-acetyl neuraminic acid of platelet thrombogenesis induced by laser injury to rat and hamster venules.

By G V Born and I B Kovács


1 In rats and hamsters under barbiturate anaesthesia, laser radiation to venules about 50 micrometer in diameter in mesoappendix and cheek pouch respectively caused the formation of platelet thrombi which occluded the vessels in about 9 min. 2 This occlusion time was significantly prolonged by the intravenous injection of N-acetyl neuraminic acid (NANA) but not by D-glucuronic acid or beta-methoxyneuraminic acid, in doses which had no effect on blood pH or on the condition of the animals. 3 The results confirm the anti-thrombotic effect of NANA previously demonstrated with another technique

Topics: Research Article
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.