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THE REACTION OF 2-SUBSTITUTE OF ADAMANTHANE WITH NITRIC ACID AND ITS MIXTURES

By Marina Valentinovna Leonova

Abstract

The object of investigation: the 2-substitute and 2,2-disubstitute of adamanthane. The influense of the character of the substitute and the type of the reaction medium on chemo- and regioselectivity of the nitriumxylirating 2-substitute adamanthane has been established. The preparative methods of synthesis of the nitroxy-, hydroxy, acetylamino- and aminoderivatives on the base of 2-substitute of adamanthane have been developed. The comparative reaction ability of the 2-substitute in the reaction with nitric acid has been studied. The new synthetic approach to the synthesis of the hard-to-access hemdisubstitute of adamanthane and 2-X-2-adamanthanecarbonic acids has been developed. The antivirus and psychotropic activity of the number of the synthesized compounds has been revealedAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

Topics: 07C - Organic chemistry, CHEMISTRY
Year: 1996
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Provided by: OpenGrey Repository
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