Exchange of the nucleic acids of lever and the blood serum lipidetransport system state with stimulation by the regenerating hypertrophy of lever

Abstract

The object of investigation: the blood serum and regenerating lever of the albino not pedigree laboratory rats. The purpose of the work: the development of method of the pharmacological stimulation of processes of the nucleic acids biosynthesis into the proliferative phase and restoration of the lipidetransport system functional state in the hyperplastic phase of regeneration of the normal and disturbed by the free radicals lever. Grounded scientifically have been the mechanisms of action of prodigiosan through the stimulation of the transcription processes in the intact lever; the processes of the DNA replication synthesis in the regenerating lever and the ability to restore the lipidetransport system parameters. The indications for application of prodigiosan and riboxin have been determined depending on the lever state. Founded has been the application of preparations in the pre-operation period at operations to be performed on the organs of the hepato-biliary system as well as stimulation of the DNA reparation synthesis at gamma-radiation in doses of 1,0 Gr order. The methods of stimulation of the lever regeneration have been introduced in the scientific investigationsAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio