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Regional Chemotherapy of the Lung: Investigations of Isolated Lung Perfusion and Selective Pulmonary Artery Perfusion

By M.J.J.H. Grootenboers


The aim of this thesis was two-fold. First, - part I of the dissertation -, to explore ILuP with melphalan and hyperthermia followed by pulmonary metastasectomy in patients with resectable pulmonary metastases. Second, - part II -, to investigate the feasibility and pharmacokinetics of SPAP with gemcitabine, studied in a tumor-free porcine model

Topics: Geneeskunde, isolated lung perfusion, pulmonary artery perfusion, melphalan, gemcitabine
Publisher: Utrecht University
Year: 2008
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