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Central monoamine metabolism in depressions. I. Serotonin and related compounds

By H.M. van Praag


This article reviews research into the possible significance of disorders of the central 5-HT metabolism in the pathogenesis of recurrent depressions. The available data would seem to warrant the tentative conclusion that such metabolic disorders are indeed involved in a certain subcategory of vital depressions and play a (possible predisposing) role in the pathogenesis of these depressions.\ud \ud The use of 5-HT precursors in depressions is regarded as a potential asset, although the conclusion that real substitution therapy can thus be given would be premature

Topics: Geneeskunde
Year: 1980
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