Escherichia coli K12 contains several so-called
major outer membrane proteins, the designation of
which was different in various laboratories but it is now agreed that the proteins will be named
according to the designation of their structural gene. The products of the ompC (min 48) and ompF
(min 21) genes, formerly designated as c and b in our
laboratory, are outer membrane proteins
which function as aqueous pores through which many
nutrients enter the cell via a diffusion-like process. Mutants which lack both the ompC and ompF
products are sensitive to 3% sodium dodecyl sulphate
(SDS
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