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Re-Evaluating Cell-Cycle Regulation by E2Fs

By R.A. Bernards and B.D. Rowland


Activation of E2F transcription factors is thought to drive the expression of genes essential\ud for the transition of cells from G1 to S phase and for the initiation of DNA replication.\ud However, this textbook view of E2Fs is increasingly under challenge. Here we discuss an\ud alternative model for how E2Fs may work

Topics: Biologie
Year: 2006
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