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Prostaglandin action on pancreatic blood flow and on electrolyte and enzyme secretion by exocrine pancreas in vivo and in vitro

By R. M. Case and T. Scratcherd


1. Intra-arterial injection or infusion of prostaglandins E1 and E2 into anaesthetized cats caused a fall in arterial blood pressure, a reduction in pancreatic blood flow and an inhibition of secretin-stimulated pancreatic electrolyte secretion. In some experiments these effects were preceded by a transient increase in blood flow and secretion

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