research article
β-catenin in reverse action
Abstract
Motor neurons and muscle fibers interact in complex ways to build the neuromuscular synapse. A new study shows that β-catenin is required in muscle to provide an unknown retrograde signal that is necessary for presynaptic transmitter release. © 2008 Nature Publishing Group.link_to_subscribed_fulltex- Article
- Chemicals And Cas Registry Numbers: Beta Catenin
- Receptors, Cholinergic
- Wnt Proteins
- Animals
- Cell Communication - physiology
- Cell Differentiation - physiology
- Humans
- Mice
- Mice, Knockout
- Motor Neurons - metabolism
- Muscle, Skeletal - embryology - innervation
- Neuromuscular Junction - embryology
- Presynaptic Terminals - metabolism - ultrastructure
- Receptor Aggregation - physiology
- Receptors, Cholinergic - metabolism
- Signal Transduction - physiology
- Wnt Proteins - genetics - metabolism
- beta Catenin - metabolism
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This paper was published in HKU Scholars Hub.
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