Article thumbnail
Location of Repository

Estimation of gamma globulin in the serum of patients with hypogammaglobulinaemia

By R. A. Kekwick, L. Vallet, M. Cutbush, P. L. Mollison, A. R. Thomas, P. G. H. Gell and J. F. Soothill

Abstract

Three methods of estimating γ globulin in the serum of patients with hypogammaglobulinaemia are described and compared, namely free electrophoresis, the inhibition of antiglobulin antiserum method, and the gel diffusion precipitin method. Data from 142 parallel estimations are reported. The errors of these methods are determined. The results of the three techniques give good general agreement. This is due to the fact that the 7S component dominates the estimations whichever technique is used. Some discrepancies are discussed. All of the techniques are applicable to the diagnosis of hypogammaglobulinaemia. Their practical limitations are discussed

Topics: Articles
Year: 1961
DOI identifier: 10.1136/jcp.14.5.470
OAI identifier: oai:pubmedcentral.nih.gov:480265
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.