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U-42, 126, a New Antimetabolite Antibiotic: Production, Biological Activity, and Taxonomy of the Producing Microorganism

By L. J. Haňka and A. Dietz

Abstract

A new antimetabolite antibiotic, U-42,126, was discovered by use of a specific in vitro screen. U-42,126 was produced by the fermentation of Streptomyces sviceus. Its antimicrobial activity in vitro was limited to fungi. Certain bacteria were inhibited only when cultivated in completely synthetic media. U-42,126 was active in vivo against L1210 leukemia in mice

Topics: Articles
Year: 1973
DOI identifier: 10.1128/aac.3.3.425
OAI identifier: oai:pubmedcentral.nih.gov:444426
Provided by: PubMed Central
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