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RPL11, an R Factor of Pseudomonas aeruginosa Determining Carbenicillin and Gentamicin Resistance

By T. R. Korfhagen and J. C. Loper

Abstract

R factor RPL11 from Pseudomonas aeruginosa determines multiple drug resistance including resistance to gentamicin and carbenicillin. The host range and incompatibility properties of RPL11 are those of incompatibility group P-2. Strains harboring the factor are not altered with respect to the major immunotypes 1 through 7 of Parke-Davis, or with respect to pyocin type by using the 18 indicators of Jones and co-workers. Analytical ultracentrifugation of crude extracts of R factor-containing strains shows a band of satellite DNA with a buoyant density of 1.717 g/cm(3)

Topics: Articles
Year: 1975
DOI identifier: 10.1128/aac.7.1.69
OAI identifier: oai:pubmedcentral.nih.gov:429075
Provided by: PubMed Central
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