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Cholestatic liver (dys)function during sepsis and other critical illnesses

By Marc Jenniskens, Lies Langouche, Yoo-Mee Vanwijngaerden, Dieter Mesotten and Greet Van den Berghe


In ICU patients, abnormal liver tests are common. Markers of cholestasis are associated with adverse outcome. Research has focused on the possibility that mild hyperbilirubinemia, instead of indicating inadvertent cholestasis, may be adaptive and beneficial. These new insights are reviewed and integrated in the state-of-the-art knowledge on hepatobiliary alterations during sepsis and other critical illnesses.status: publishe

Publisher: Springer International
Year: 2016
DOI identifier: 10.1007/s00134-015-4054-0
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Provided by: Lirias

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