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Processing of complex heteroduplexes in Escherichia coli and Cos-1 monkey cells.

By J P Abastado, B Cami, T H Dinh, J Igolen and P Kourilsky


Upon transformation into Escherichia coli or Cos-1 monkey cells, heteroduplex DNA made of two sequences containing many nucleotide mismatches yields a wide array of different molecules, some with a patchwork structure. Thus, complex heteroduplexes can be processed to generate many genetic variants

Topics: Research Article
Year: 1984
DOI identifier: 10.1073/pnas.81.18.5792
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Provided by: PubMed Central
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