18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment : a phase 2 trial.
Abstract
The most widely studied positron emission tomography ligand for in vivo beta-amyloid imaging is (11)C-Pittsburgh compound B ((11)C-PIB). Its availability, however, is limited by the need for an on-site cyclotron. Validation of the (18)F-labeled PIB derivative (18)F-flutemetamol could significantly enhance access to this novel technology- info:eu-repo/semantics/article
- Aged
- Alzheimer Disease - radionuclide imaging
- Radiopharmaceuticals - diagnostic use
- Sensitivity and Specificity
- Benzothiazoles - diagnostic use
- Brain - metabolism, radionuclide imaging
- Cognition Disorders - radionuclide imaging
- Diagnostic Imaging
- Fluorodeoxyglucose F18 - analogs & derivatives, diagnostic use
- Humans
- Middle Aged
- Positron-Emission Tomography - methods