Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.

Nyiraneza, Christine; Sempoux, Christine; Detry, Roger; Kartheuser, Alex; Dahan, Karin

research article

oai:dial.uclouvain.be:boreal:116219

Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.

Authors: Christine Nyiraneza
Christine Sempoux
Roger Detry
Alex Kartheuser
Karin Dahan
Publication date: 1 January 2012
Publisher: Springer
Doi

Abstract

p14ARF epigenetic silencing may represent an important deregulating mechanism of the p53-MDM2-p14ARF pathway in CRCs exhibiting a restricted p53 overexpression pattern

info:eu-repo/semantics/article

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Last time updated on 14/05/2016

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