Skip to main content
Article thumbnail
Location of Repository

Micro-indirect hemagglutination test for detection of antibodies to the Ibc protein of group B Streptococcus.

By C P Thangavelu and G Koshi


A micro-indirect hemagglutination test was developed for detecting antibody against the Ibc protein of group B Streptococcus. Formalin-preserved, tanned sheep erythrocytes were sensitized with a partially purified preparation of Ibc protein from a type Ic strain of group B streptococci. A total of 76% of 103 sera from pregnant and nonpregnant women had demonstrable antibody against this protein, with titers ranging from 10 to 320. Examination of five pairs of mother and cord sera revealed passive transfer of these antibiodies from mother to infant. This testing on a limited number of sera also revealed that elevated antibody titers against Ibc protein were more common among carriers of group B streptococci, especially those harboring strains with Ibc protein antigen, than among noncarriers. The technique described was found to be simple, specific, sensitive, and reproducible and may be of value in assessing the immune status of pregnant women as well as for epidemiological purposes

Topics: Research Article
Year: 1980
OAI identifier:
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.