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Specific binding of neoglycoproteins to Toxoplasma gondii tachyzoites.

By R Robert, P L de la Jarrige, C Mahaza, J Cottin, A Marot-Leblond and J M Senet

Abstract

Several studies have shown that protozoa bind to glycoproteins or neoglycoproteins. Here we report that Toxoplasma gondii binds strongly to bovine serum albumin-glucosamide. The binding was rapid, time dependent, partially reversible, saturable, and specific. Scatchard analysis showed about 40,000 molecules of bovine serum albumin-glucosamide per toxoplasma cell. The apparent dissociation constant was found to be 4.46 x 10(-8) M

Topics: Research Article
Year: 1991
OAI identifier: oai:pubmedcentral.nih.gov:259094
Provided by: PubMed Central
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