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Mutants of Saccharomycopsis lipolytica defective in lysine catabolism.

By C Gaillardin, P Fournier, G Sylvestre and H Heslot


Wild-type strains of Saccharomycopsis lipolytica are able to use lysine as a carbon or a nitrogen source, but not as a unique source for both. Mutants were selected that could not use lysine either as a nitrogen or as a carbon source. Some of them, however, utilized N-6-acetyllysine or 5-aminovaleric acid. Many of the mutants appeared to be blocked in both utilizations, suggesting a unique pathway for lysine degradation (either as a carbon or as a nitrogen source). Genetic characterization of these mutants was achieved by complementation and recombination tests

Topics: Research Article
Year: 1976
OAI identifier: oai:pubmedcentral.nih.gov:233334
Provided by: PubMed Central
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