Skip to main content
Article thumbnail
Location of Repository

ABNORMAL CIRCULAR DNA MOLECULES INDUCED BY ETHIDIUM BROMIDE IN THE KINETOPLAST OF Trypanosoma cruzi*

By Guy Riou and Etienne Delain

Abstract

The trypanocidal drug ethidium bromide induced abnormal circular DNA molecules with high frequency in the kinetoplast of Trypanosoma cruzi. These molecules are circular dimers, trimers, or higher circular forms with a contour length which is a multiple of the monomer length usually found in the kinetoplastic DNA of normal trypanosomes. These abnormal molecules represent more than 30 per cent of the kinetoplastic DNA, while in normal kinetoplastic DNA we only observed three circular dimers out of several thousand molecules measured

Topics: Biological Sciences: Biochemistry
Year: 1969
OAI identifier: oai:pubmedcentral.nih.gov:223389
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.