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Fertility inhibition of RP1 by IncN plasmid pKM101.

By S C Winans and G C Walker


IncN plasmids, including pKM101, strongly inhibit the conjugal transfer of cohabiting IncP plasmids. We localized the pKM101 DNA sufficient for this phenomenon to a 1.1-kilobase region (denoted fip). Two fip-deficient Tn5 insertion derivatives of pKM101 were isolated; neither affected other pKM101-mediated functions. fip did not inhibit either the synthesis of the IncP plasmid's sex pilus or its ability to mediate entry exclusion against other IncP plasmids

Topics: Research Article
Year: 1985
OAI identifier: oai:pubmedcentral.nih.gov:214888
Provided by: PubMed Central
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