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Positive regulation of the Escherichia coli glycine cleavage enzyme system.

By R L Wilson, P S Steiert and G V Stauffer


A new mutation in Escherichia coli, designated gcvA1, that results in noninducible expression of both gcv and a gcvT-lacZ gene fusion was isolated. A plasmid carrying the wild-type gcvA gene complemented the mutation and restored glycine-inducible gcv and gcvT-lacZ gene expression. These results suggest that gcvA encodes a positive-acting regulatory protein that acts in trans to increase expression of gcv

Topics: Research Article
Year: 1993
DOI identifier: 10.1128/jb.175.3.902-904.1993
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Provided by: PubMed Central
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