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Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.

By H Machida

Abstract

The susceptibilities of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) to 17 nucleoside analogs were compared by a plaque reduction assay with human embryonic lung fibroblast cells. The susceptibility of VZV to certain nucleoside analogs was different from that of HSV-1. Against VZV the 5-halogenovinyl-arabinosyluracils were the most potent of the compounds tested

Topics: Research Article
Year: 1986
OAI identifier: oai:pubmedcentral.nih.gov:180428
Provided by: PubMed Central
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