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Nucleotide sequence of SHV-2 beta-lactamase gene.

By A Garbarg-Chenon, V Godard, R Labia and J C Nicolas


The nucleotide sequence of plasmid-mediated beta-lactamase SHV-2 from Salmonella typhimurium (SHV-2pHT1) was determined. The gene was very similar to chromosomally encoded beta-lactamase LEN-1 of Klebsiella pneumoniae. Compared with the sequence of the Escherichia coli SHV-2 enzyme (SHV-2E.coli) obtained by protein sequencing, the deduced amino acid sequence of SHV-2pHT1 differed by three amino acid substitutions

Topics: Research Article
Year: 1990
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Provided by: PubMed Central
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