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Susceptibility of Nocardia asteroides to new quinolones and beta-lactams.

By M E Gombert, T M Aulicino, L duBouchet and L R Berkowitz


The susceptibility of 31 strains of Nocardia asteroides to various quinolones and beta-lactams, as well as coumermycin, amikacin, and minocycline, was determined by the agar dilution technique. Ciprofloxacin was the most active fluoroquinolone tested on a weight basis, as it inhibited approximately 50% of the isolates at achievable drug levels in serum. Ceftriaxone and cefpirome were the most active cephalosporins in this system with MICs of 8 micrograms/ml for 80% of strains tested. Imipenem, amikacin, and minocycline were the most effective agents tested

Topics: Research Article
Year: 1987
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Provided by: PubMed Central
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