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Immune response to Shigella sonnei in U.S. Marines.

By M M Mikhail, M M Mansour, B A Oyofo and J D Malone


Pre- and postdeployment serum samples obtained from U.S. marines in Operations Desert Shield and Desert Storm were tested for antibodies to Shigella sonnei. High predeployment levels of immunoglobulin A (IgA) and/or IgG antibodies to S. sonnei lipopolysaccharide antigen in serum and seroconversions were accompanied by higher IgA and/or IgG antibody response to Shigella invasion plasmids (Ipa). The results suggest exposure to S. sonnei in predeployment troops and frequent exposure to this bacterial agent during deployment

Topics: Research Article
Year: 1996
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Provided by: PubMed Central
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