Article thumbnail
Location of Repository

Discordance between T-Cell Receptor Expression and Effector Function in Mice Infected with Histoplasma capsulatum

By George S. Deepe, Reta S. Gibbons and Susan R. Ward


Vβ10(+) and Vβ14(+) T cells were selectively increased 7 to 14 days following infection in the lungs of naive mice infected with Histoplasma capsulatum. Following secondary challenge of immune mice, Vβ1(+) and Vβ8.1(+) cells were sporadically increased. Elimination of Vβ10(+) and Vβ14(+) cells from naive mice did not alter the course of infection over a period of 21 days. Thus, overexpression of Vβ families does not necessarily signify a key role in host defense

Topics: Fungal and Parasitic Infections
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/IAI.70.3.1648-1652.2002
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.