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Production of Prostaglandins and Leukotrienes by Pathogenic Fungi

By Mairi C. Noverr, Galen B. Toews and Gary B. Huffnagle

Abstract

These studies demonstrate that pathogenic fungi (dermatophytic, subcutaneous, and systemic) have the ability to produce eicosanoids both from simple metabolites and from arachidonic acid. Host-derived eicosanoids have been previously demonstrated to enhance fungal colonization and atopic disease development. Thus, fungus-derived eicosanoids represent a potential class of novel virulence factors

Topics: Fungal and Parasitic Infections
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/IAI.70.1.400-402.2002
OAI identifier: oai:pubmedcentral.nih.gov:127633
Provided by: PubMed Central
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