Location of Repository

Intracellular Crystal Formation as a Mechanism of Cytotoxicity in Murine Pulmonary Cryptococcus neoformans Infection

By Marta Feldmesser, Yvonne Kress and Arturo Casadevall

Abstract

Rod-like crystalline structures formed during eosinophilic Cryptococcus neoformans pneumonia in C57BL/6 mice. Crystals were found associated with yeast cells and free in host cell cytoplasm. The crystals apparently formed because of the interaction of a host protein with the cryptococcal polysaccharide. Crystal formation likely contributes to pathogenesis by causing cellular damage

Topics: Fungal and Parasitic Infections
Publisher: American Society for Microbiology
Year: 2001
DOI identifier: 10.1128/IAI.69.4.2723-2727.2001
OAI identifier: oai:pubmedcentral.nih.gov:98213
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dx.doi.org/10.1128/IAI.... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.