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Streptococcus pneumoniae Isolates with Reduced Susceptibility to Ciprofloxacin in Spain: Clonal Diversity and Appearance of Ciprofloxacin-Resistant Epidemic Clones

By Luis Alou, Mario Ramirez, César García-Rey, José Prieto and Hermínia de Lencastre

Abstract

Analysis of the pulsed-field gel electrophoretic profiles of 82 pneumococcal isolates with reduced susceptibility to ciprofloxacin (RSC) and of 90 co-occurring susceptible isolates indicates a considerable genetic diversity among isolates with RCS and points to a close relation between the two groups. This finding suggests that pneumococci with RCS emerge through independent mutational events

Topics: Mechanisms of Resistance
Publisher: American Society for Microbiology
Year: 2001
DOI identifier: 10.1128/AAC.45.10.2955-2957.2001
OAI identifier: oai:pubmedcentral.nih.gov:90763
Provided by: PubMed Central
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