The overall aim of the BioSimGrid project (www.biosimgrid.org) is to exploit the Grid infrastructure to enable comparative analysis of the results of biomolecular simulations. In particular this paper discusses the security implementation of the BioSimGrid web portal. To achieve a secured application environment, a dedicated security layer has been built on the layers of SOA (Service Oriented Architecture) framework. The security module integrates PKI (Public Key Infrastructure) and supports two levels of authentication: Grid certificate-based authentication for high security, and user/pass based authentication for maximal flexibility
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